Gabriel S. Jacobs's avatar

Gabriel S. Jacobs

@gsjphd.bsky.social

I guess it's technically okay to collect data before formulating hypotheses so long as you absolutely 100% do NOT look at them, but even that's iffy. If you do a 1-tailed t-test but pick which tail AFTER you collect your data, you've really done a 2-tailed t-test (but falsely halved your p-value).

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Unfork Statistics's avatar Unfork Statistics @btjo.bsky.social
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You can look at your data any which way you like, with or without pre-specified hypotheses. But if you didn't prespecify (or you prespecified a fishing trip with dozens of tests), you have not tested the hypothesis, you have generated it. As long as you don't lie about it, you can do what you want.

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Ed Rybicki πŸ‡ΏπŸ‡²πŸ‡ΏπŸ‡¦πŸ·πŸš€'s avatar Ed Rybicki πŸ‡ΏπŸ‡²πŸ‡ΏπŸ‡¦πŸ·πŸš€ @edrybicki.bsky.social
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Thank Fork that we mostly do things that simply require us to know β€œIs it there as DNA?”, and if it is, β€œDoes it express as protein?”. And if the answer to either question is β€œNo”, rinse/repeat!

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