While DOJ independence was already a dead letter for purposes of a second Trump term since Attorney General E. Trump or J. Turley or whoever will have been chosen expressly because he's willing to take orders, also worth noting that Roberts blessed POTUS telling AG whom to prosecute.
First up though will be Sotomayor, Kagan, and Jackson. Need to clear the bench to have a conservative novem after replacing Alito and Thomas with 40 year old versions of them.
On one hand, this sucks. A lot. On the other hand, I'm cynical enough to think he mostly doesn't go after these targets just so he and allies in the media can say people are overreacting when they do a bunch of other personal prosecutions for other individuals.