: "Cool thing: One of the other companies who were helping the effort devised a forensic SNP panel. SNPs are great, because you don't need nearly as much contiguous DNA to find them as with STRs. Then we had to make an efficient many-to-many matching algorithm. *Amazing* to see it work the first time."

@puzzlescarves.bsky.social

Cool thing: One of the other companies who were helping the effort devised a forensic SNP panel. SNPs are great, because you don't need nearly as much contiguous DNA to find them as with STRs. Then we had to make an efficient many-to-many matching algorithm. *Amazing* to see it work the first time.

May 10, 2024 at 00:59 UTC

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@puzzlescarves.bsky.social
[ View ] May 10, 2024 at 23:30 UTC

Oh, and by "amazing", I mean this: There were STR (old-style) DNA profiles where, of the 13 sites + gender marker, only the gender marker was there. And it turned out to be wrong. Which we knew because from SNP panel an analyst could identify them confidently.

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@puzzlescarves.bsky.social
[ View ] May 10, 2024 at 01:02 UTC

Though also ridiculously garish. Boss: "Use these exact colors for SNPs. I want them so ugly customer will *have* to specify the real ones." Customer: "Yup, can see exactly what's going on from across the room. 10/10, no notes." (We tested on that week's new data, because what else was there.)

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