bioRxivpreprint

bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:32 UTC

Maternal obesity and offspring neurodevelopment are associated with hypoxic gene expression in term human placenta www.biorxiv.org/content/10.1101/2024.07.10.602900v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:31 UTC

Structural constraints and drivers of molecular evolution in a macromolecular complex; the kinetochore www.biorxiv.org/content/10.1101/2024.07.10.602950v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:16 UTC

Golgi cells regulate timing and variability of information transfer in a cerebellar-behavioural loop www.biorxiv.org/content/10.1101/2024.07.10.602852v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:16 UTC

Cerebellar contribution to cognitive deficits and prefrontal cortex dysfunction in Spinocerebellar Ataxia Type 1 (SCA1) www.biorxiv.org/content/10.1101/2024.07.10.602931v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:15 UTC

Striatal endocannabinoid-long-term potentiation mediates one-shot learning www.biorxiv.org/content/10.1101/2024.07.10.602953v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:15 UTC

Functional ultrasound imaging and neuronal activity: how accurate is the spatiotemporal match? www.biorxiv.org/content/10.1101/2024.07.10.602912v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:15 UTC

Neuronal Hyperactivity in Neurons Derived from Individuals with Grey Matter Heterotopia www.biorxiv.org/content/10.1101/2024.07.10.602948v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:15 UTC

Developmental dynamics of the prefrontal cortical SST and PV interneuron networks: Insights from the monkey highlight human-specific features www.biorxiv.org/content/10.1101/2024.07.10.602904v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 06:15 UTC

Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposure www.biorxiv.org/content/10.1101/2024.07.10.602959v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:47 UTC

Molecular bases and specificity behind the activation of the immune system OAS/RNAse L pathway by viral RNA. www.biorxiv.org/content/10.1101/2024.07.08.602453v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:33 UTC

Comparative genomics reveals diversity and taxonomic relationships among Clostridioides difficile phages www.biorxiv.org/content/10.1101/2024.07.10.602917v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:33 UTC

Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice www.biorxiv.org/content/10.1101/2024.07.08.602428v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:32 UTC

Mapping the Global Distribution of Mus musculus: Implications for Evolutionary Genetics www.biorxiv.org/content/10.1101/2024.07.09.602589v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:31 UTC

Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue www.biorxiv.org/content/10.1101/2024.07.09.602788v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:19 UTC

Newborn reactions to maternal prenatal stress alter umbilical cord blood tRNA fragments targeting cholinergic transcripts www.biorxiv.org/content/10.1101/2024.07.10.602894v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:18 UTC

TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro www.biorxiv.org/content/10.1101/2024.07.10.602849v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:18 UTC

In vivo tests of the E. coli TonB system working model:interaction of ExbB with unknown proteins, identification of TonB-ExbD transmembrane heterodimers and PMF-dependent ExbD structures. www.biorxiv.org/content/10.1101/2024.07.10.602958v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:17 UTC

A porcine chronic hepatitis E virus (HEV) infection model exhibits HEV replication in male accessory reproductive glands and immune-mediated reproductive damage www.biorxiv.org/content/10.1101/2024.07.10.602840v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:17 UTC

QuickFit: A high-throughput RT-qPCR-based assay to quantify viral growth and fitness in vitro www.biorxiv.org/content/10.1101/2024.07.08.602587v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:17 UTC

A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor www.biorxiv.org/content/10.1101/2024.07.10.602945v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:17 UTC

Reconstruction and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate www.biorxiv.org/content/10.1101/2024.07.09.602819v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:16 UTC

Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model www.biorxiv.org/content/10.1101/2024.07.10.602898v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:16 UTC

Dynamics of bacterial biofilm development imaged using light sheet fluorescence microscopy www.biorxiv.org/content/10.1101/2024.07.10.602771v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:16 UTC

Environmental differences impact Acinetobacter baumannii phage isolation and infectivity www.biorxiv.org/content/10.1101/2024.07.10.602838v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:15 UTC

Engineering programmable CAR-T cells with tunable controls as fail-safe mechanisms during cancer immunotherapy www.biorxiv.org/content/10.1101/2024.07.09.602762v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 05:03 UTC

Mobius Assembly for Plant Systems uncovers combinatorial interactions among promoters, coding sequences, and terminators in gene regulation www.biorxiv.org/content/10.1101/2024.07.10.602858v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:47 UTC

Atomistic Prediction of Structures, Conformational Ensembles and Binding Energetics for the SARS-CoV-2 Spike JN.1, KP.2 and KP.3 ... www.biorxiv.org/content/10.1101/2024.07.09.602810v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:45 UTC

NMR Reveals the Synergistic Roles of Bivalent Metal Ions in Norovirus Infections www.biorxiv.org/content/10.1101/2024.07.10.602906v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:45 UTC

The structural and biophysical basis of substrate binding to the hydrophobic groove in Ubiquilin Sti1 domains www.biorxiv.org/content/10.1101/2024.07.10.602902v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:32 UTC

Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing www.biorxiv.org/content/10.1101/2024.07.10.599183v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:32 UTC

Post-transcriptional cross- and auto-regulation buffer expression of the human RNA helicases DDX3X and DDX3Y www.biorxiv.org/content/10.1101/2024.07.08.602613v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:18 UTC

50 years of antibody numbering schemes: a statistical and structural evaluation reveals key differences and limitations www.biorxiv.org/content/10.1101/2024.07.08.602590v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:18 UTC

Importin alpha inhibitors act against the differentiated stages of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii www.biorxiv.org/content/10.1101/2024.07.10.602875v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:18 UTC

A unique mechanism of snRNP core assembly www.biorxiv.org/content/10.1101/2024.07.09.602679v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:18 UTC

A Transfection-Free Approach of Gene Editing via a gold-based nanoformulation of the Cas9 protein www.biorxiv.org/content/10.1101/2024.07.09.602746v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:17 UTC

Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits www.biorxiv.org/content/10.1101/2024.07.10.602881v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:17 UTC

Temperate bacteriophage induced in Pseudomonas aeruginosa biofilms can modulate bacteriophage and antibiotic resistance www.biorxiv.org/content/10.1101/2024.07.10.602839v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:17 UTC

Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation www.biorxiv.org/content/10.1101/2024.07.10.602937v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:16 UTC

Star-polymers as potent broad-spectrum extracellular virucidal antivirals www.biorxiv.org/content/10.1101/2024.07.10.602907v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:16 UTC

Pleiotropic regulation of bacterial toxin production and Allee effect govern microbial predator-prey interactions www.biorxiv.org/content/10.1101/2024.07.10.602915v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:16 UTC

N-acylethanolamine acid amidase inhibition reduces SARS-CoV-2 infection in Human Precision cut-lung slices and downregulates NF-kappaB signalling. www.biorxiv.org/content/10.1101/2024.07.10.602842v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:16 UTC

Polysaccharide quantification using microbial enzyme cocktails www.biorxiv.org/content/10.1101/2024.07.10.602880v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:15 UTC

Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain www.biorxiv.org/content/10.1101/2024.07.10.602843v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 03:04 UTC

Global siRNA Screen Reveals Critical Human Host Factors of SARS-CoV-2 Multicycle Replication www.biorxiv.org/content/10.1101/2024.07.10.602835v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 02:32 UTC

Genome assembly of a diversity panel of Chenopodium quinoa www.biorxiv.org/content/10.1101/2024.07.07.602379v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 01:46 UTC

VISUALIZING GAUSSIAN-CHAIN LIKE STRUCTURAL MODELS OF HUMAN alpha-SYNUCLEIN IN MONOMERIC PRE-FIBRILLAR STATE: SOLUTION SAXS DATA AND MODELING ANALYSIS www.biorxiv.org/content/10.1101/2024.07.07.602212v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 01:31 UTC

Characterization of eight new Hydractinia i-cell markers reveals underlying heterogeneity in the adult pluripotent stem cell population www.biorxiv.org/content/10.1101/2024.07.07.602406v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 01:15 UTC

Neural correlates of phenomenological attitude toward perceptual experience www.biorxiv.org/content/10.1101/2024.07.07.602347v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 01:04 UTC

Hotspot of Exotic Benthic Marine Invertebrates Discovered in the Tropical East Atlantic: DNA Barcoding Insights from the Bijagos Archipelago, Guinea-Bissau www.biorxiv.org/content/10.1101/2024.07.07.602388v1

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bioRxivpreprint @biorxivpreprint.bsky.social [ View ] Jul 11, 2024 at 00:49 UTC

Molecular dynamics investigation of the influenza hemagglutinin conformational changes in acidic pH www.biorxiv.org/content/10.1101/2024.07.07.602399v1

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