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Allen Institute

@alleninstitute.bsky.social

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The Allen Institute is committed to solving mysteries of bioscience — researching the unknown of human biology, in the brain, the cell and the immune system.


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Celebrate the mysteries of the brain with us! 🔎🧠

At #TheBrainIDK, you'll get to do hands-on activities, get up close with real brain tissues, and chat with scientists investigating some of the toughest questions in neuroscience.

🎟️ RSVP for free: alleninstitute.org/events/2024_...

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We're counting down the days until TReND's workshop in Rwanda!

@sejdevries.bsky.social is part of an Allen Institute team making the journey to CMU Africa. Alongside others, she'll be showing students how to use our open science resources.

More about TReND-CaMinA: trendinafrica.org/trend-camina...

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Less than a week to apply for the #LakeConference on Comparative and Evolutionary Neurobiology! Accepted applicants will join discussions and presentations on emerging topics alongside the beautiful shores of Lake Washington and Lake Union.

More:
alleninstitute.org/events/lake-...

#neuroskyence

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Deadline extended for TEMTIA 11!

Register by June 28 for to attend the annual meeting of the EMT (epithelial to mesenchymal transition) International Association on Nov. 12-15.

Learn more and register at:
alleninstitute.org/events/temti...

#TEMTIA11

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Former employees and interns are invited to RE:CONNECT - an open house for Allen Institute alumni!

Meet other alumni, learn about our latest research, discover new public programs, and take home some fresh Allen Institute swag.

Get more info and RSVP:
alleninstitute.org/events/recon...

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One in 500 people have hypertrophic cardiomyopathy – the most common genetic heart condition in the world.

Today we launched a set of tools to accelerate research into this global health issue.

Meet the new cell line collections:
alleninstitute.org/news/allen-i...

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Whole, healthy human brain data is now on the ABC Atlas!   
  
Dataset incl. 3 million+ cells sampled from dissections from adult donors. Samples underwent snRNA sequencing and were clustered and categorized by neurotransmitter, region, and more. 
  
ABC Atlas: portal.brain-map.org/atlases-and-...

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We've joined Weill Neurohub, a research network advancing treatments for neurological diseases. The partnership will integrate our robust brain mapping and recording with research at UC Berkeley, UCSF, and UW. 

Learn more about this exciting new partnership:
alleninstitute.org/news/allen-i...

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Neurons interact with each other at synapses, but mapping exactly which are connected remains a challenge. A new study co-led by Aixin Zhang and Lei Jin shows how RNA barcoded rabies viruses could help researchers understand these connections.
 
Read the paper: elifesciences.org/articles/87866

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Educators - share with your students how scientists study Alzheimer's disease pathology with our "Understanding Alzheimer's Disease" curriculum. Includes 4 lesson plans and interactive image dataset of immunolabeled brain tissue. 🔗
alleninstitute.org/resource/und...

#SciEd #EndAlz

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Join us on July 15-17 for a hands-on workshop on how to use open-source software modeling tools to build, simulate, and visualize bio-realistic models of brain circuits.

No cost to participate. Applications due by 3/15.

Learn more and apply:
alleninstitute.org/events/2024-...

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As you age, so does your immune system. 🤒

Study in Nature Immunology finds that as people age, their T cells undergo molecular changes. The study used TEA-seq, a new method that analyzes immune cells at high detail, to compare immune systems.

👉
alleninstitute.org/news/how-you...

#Immunology

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We're going to be at #BPS2024 and we'd love to meet you! Swing by booth 301 and share with us what you are working on and how we can help you decode the cell.

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Educators, download lesson plans and other teaching resources for neuroscience, cell biology, and immunology in our Education Materials Library - no library card needed!

#AllenLearn

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Last night at the Northwest Science Writers Association's "Best of the Northwest" ceremony, our LabNotes podcast episode "Cracking the Code of Addiction" received an Honorable Mention in the Multimedia Writing category!

Listen to this critically acclaimed episode: alleninstitute.org/news/lab-not...

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The first complete mammalian brain cell type atlas, the interior design of human cells and more – we are understanding life and advancing health.
 
Discover how in our 2023 annual report: alleninstitute.org/news/20-year...

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Science Friday 's avatar Science Friday @scifri.bsky.social
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We're one step closer to understanding the complexity of the human brain. On today's podcast episode, Dr. Ed Lein, from the @alleninstitute.bsky.social , joins us to discuss an impressively detailed map of human brain cells released last year.

Listen here 🎧:
pod.link/73329284

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Reposted by Allen Institute

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There is a treasure trove of neuroscience data waiting to be explored by the next generation. ✨🔭🧠

Recent non-neuroscience PhDs can now apply for a three-year fellowship, working w/ neuroscientists from Allen Institute and UW.

⏳ Applications due 2/1.

More: alleninstitute.org/careers/inte...

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Check out this new study published in Nature by @hadivafaii.bsky.social et al. on using multiple methods to uncover common and divergent patterns of cortical functional organization - using the Allen Mouse Brain Common Coordinate Framework!

#AllenImpact

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Happy birthday to our partners in open science! 🧫✨

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There is a treasure trove of neuroscience data waiting to be explored by the next generation. ✨🔭🧠 Recent PhDs from non-neuroscience fields can now apply for a three-year fellowship, working with neuroscientists from Allen Institute and University of Washington.

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Over the past two decades, we have pioneered big, team, and open science approaches to understand life and advance health. Resources developed by the Institute have empowered researchers to ask bold questions about biology and propel science forward.

🎬 youtu.be/6fKn9DsJuqA

#Allen20 #AllenImpact

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🎧 Our scientists are working to understanding human cells holistically & dynamically to predict & understand health & disease. Progress, Potential, and Possibilities interviews Susanne Rafelski at the Allen Institute for Cell Science to learn more.

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They found that dopamine released not just in response to target actions, but also to those that occurred seconds before. Think of how pets learn the body language and behavior preceding you feeding them, like opening a drawer. 

@natureportfolio.bsky.social

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To investigate, Allen Institute, Columbia University's Zuckerman Mind Brain Behavior Institute, Seattle Children's Research Institute, and Champalimaud Centre for the Unknown researchers & engineers developed a new “closed loop” system that linked specific behaviors to real-time dopamine release.

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🐶🦴 Train a dog to sit and something funny occurs. They test what counts as "sit". Halfway? For 2 seconds?  
  
In Nature, researchers, incl. our President and CEO Rui Costa, share how dopamine guides animals to home in on the specific behaviors that lead to reward.

@natureportfolio.bsky.social

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The first cellular map of a mammalian brain is here. 🧠✨

Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity.  

Dive deeper: alleninstitute.org/scientists-u..

#studyBRAIN

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MapMyCells has been updated with new features, algorithms, and its first human reference dataset - a high-res transcriptomic cell type atlas of the middle temporal gyrus spanning the Alzheimer’s disease spectrum.

Explore MapMyCells: portal.brain-map.org/atlases-and-...

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On this day in 2018, the Allen Institute for Immunology was founded with the mission to apply the Institute's big science and team science approach to understanding the dynamic human immune system. #Allen20

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Happy Birthday to the Allen Institute for Cell Science! 🥳🎂

On this day in 2014, the Allen Institute for Cell Science was founded to investigate and model the complex living machinery of cells.

#Allen20

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Today with the Chan Zuckerberg Initiative and UW Medicine, we’re launching the Seattle Hub for Synthetic Biology (#SeaSynBio), a first-of-its-kind research initiative that will reimagine how we study cells by turning them into their own recording devices. 

More: alleninstitute.org/news/seattle...

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Describe your neurons like the Allen Institute! 🧠✨

Join us Apr. 8-10 for a free workshop in Seattle! Learn how we define “cell types” and practical ways to apply our resources and tools to your research. Travel support available.

👉 Apply by Jan. 8:
alleninstitute.org/events/describe_your_neurons/

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On this day in 2016, the Allen Institute for Cell Science released the Allen Cell Collection, the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key structures.

#Allen20 #cellbio2023 #openscience

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What are the biological properties of extracellular vesicles? How do sex hormones drive behavior and development? With $10.5M in total research funding, 18 newly announced Allen Distinguished Investigators will help move this #FrontierScience forward.

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