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Stacey Ogden π¦
@labogden.bsky.social
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Yes - notochord and floor plate both produce and release SHH at this stage.
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Stacey Ogden π¦@labogden.bsky.social |
779 followers 1042 following 254 posts
Cell and Developmental Biologist at St. Jude Children's Research Hospital - I post about science, academia, lab research, lab dynamics, mentoring, science communication, birds, and my dogs - Fueled by π§πΌββοΈ and β - Views my own.
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Stacey Ogden π¦
@labogden.bsky.social
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Yes - notochord and floor plate both produce and release SHH at this stage.
0 replies 0 reposts 2 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Happy #FluorescenceFriday! This is an image of a developing neural tube showing the expression pattern of my favorite morphogen, Sonic Hedgehog (green)! #DevBio Image by @erichall.bsky.social and @miriamdillard.bsky.social π§ͺ π©βπ¬ π¬
2 replies 9 reposts 26 likes
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Oded Rechavi
@odedrechavi.bsky.social
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"Pay for Open Access, I don't care how much it costs"
1 replies 9 reposts 29 likes
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Stacey Ogden π¦
@labogden.bsky.social
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I'm happy to share a new paper from the lab! π₯³ This study, led by Shariq Ansari, shows that Sonic Hedgehog stimulates crosstalk between primary cilium localized Smoothened and EP4 to balance ciliary cAMP and prevent primary cilium shortening. #DevBio π§ͺ
rupress.org/jcb/article/...
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Stacey Ogden π¦
@labogden.bsky.social
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Some shots from my visit to the country (aka my momβs neighborhood) πͺΆ 1. Song sparrow 2. House wren 3. Cooperβs hawk 4. Mallards All shots taken with a Nikon Coolpix P950.
1 replies 0 reposts 11 likes
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Stacey Ogden π¦
@labogden.bsky.social
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New birding camera arrived πͺΆ 1. Cooperβs Hawk 2. American Kestrel perched on top of a satellite tower
2 replies 0 reposts 9 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Had a leucistic brown headed cowbird visit the feeder today. Not super excited about cowbirds showing upβ¦but it was cool to see a leucistic bird up close πͺΆ
0 replies 0 reposts 4 likes
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Stacey Ogden π¦
@labogden.bsky.social
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TFW you're looking for cytonemes and you find a seahorse π€ I hope you have a great #fluorescencefriday! Image by St. Jude graduate student Christina Wang. #devbio π§ͺ π©βπ¬
1 replies 0 reposts 17 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Spotted two Mississippi kites while walking the dogβ¦followed them to a treeβ¦and then one of them pooped on me πͺΆ Iβm taking it as a good luck omen π
2 replies 0 reposts 7 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Spotted a colony of nesting herons π€© πͺΆ
1 replies 1 reposts 14 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Iβm a big fan of the shorebirds. I could watch them all day π πͺΆ
1 replies 0 reposts 13 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Heading to Santa Rosa Beach, FL for a yoga retreat and to do some birding πͺΆ (still w/out a βgoodβ camera π). Need this battery recharge πͺ« π§πΌββοΈποΈπ¦©
0 replies 0 reposts 1 likes
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Stacey Ogden π¦
@labogden.bsky.social
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HUGE congratulations to Rhodes College UNDERGRAD researcher Chris Hom, who defended his Senior Honors Thesis on phospho-regulation of BOC. Chris is the REAL DEAL so admit him if he applies to your PSTP program! π¨π»βπ¬π¨π»βπ π§ͺPhotos w/his lab mentors Christina Daly & Tanu Pandit.
0 replies 2 reposts 5 likes
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Stacey Ogden π¦
@labogden.bsky.social
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It's a rainy day at St. Jude in Memphis, so here is a science rainbow to chase the clouds away. This is a SciArt piece by former postdoc Suresh Marada. Image shows a Drosophila egg chamber pseudocolored using photoshop. Happy Microscopy Monday! π§ͺ π©βπ¬
1 replies 1 reposts 11 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Mallard πͺΆ
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Stacey Ogden π¦
@labogden.bsky.social
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Juvenile eastern bluebirds πͺΆ
1 replies 0 reposts 11 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Birding friends - I'm looking for suggestions for a good birding camera with decent zoom. I don't need National Geographic quality pictures - I just want to take nice pictures of the birds we see on our outings. Any info appreciated! πͺΆ
2 replies 1 reposts 1 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Weekend birding excitement - spotted 2 pair of black-bellied whistling ducks! 1st encounter for me - South Memphis Ensley Engineer Yard. πͺΆ
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Stacey Ogden π¦
@labogden.bsky.social
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Male and female eastern blue birds πͺΆ
0 replies 1 reposts 14 likes
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Ed Yong
@edyong209.bsky.social
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I wrote a little essay about what birding has done for me in the very short time since I became a birder.
Gift link: www.nytimes.com/2024/03/30/o...
72 replies 255 reposts 999 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Our Saturday owl prowl through Overton Park was a success! π¦ We spotted THREE owls on a tree together! They had a short meeting and then flew off in different directions to hunt πͺΆ
0 replies 1 reposts 4 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Woodpeckers Iβve spotted in Memphis parks this month: 1. Hairy 2. Downy 3. Red-bellied 4. Red-headed (!) 5. Northern Flicker 6. Pileated ππΌ πͺΆ
0 replies 2 reposts 15 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Happy #FluorescenceFriday! This is a montage of neural tube sections stained for SHH target genes Olig2 and Pax6. Stains and imaging by Lab Manager @miriamdillard.bsky.social; montage by scope wizard @alexcarisey.bsky.social π§ͺ
0 replies 5 reposts 12 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Barred Owl πͺΆ Overton Park in Midtown Memphis
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Stacey Ogden π¦
@labogden.bsky.social
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Happy #InternationalWomansDay from the women of the Ogden Lab! Iβm lucky to work with such a strong group of women in STEM! π π©π»βπ¬ π§ͺ
0 replies 1 reposts 11 likes
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Stacey Ogden π¦
@labogden.bsky.social
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New cytoneme paper just dropped on @biorxivpreprint.bsky.social! The authors identified the kinase Slik as a regulator of cytoneme biogenesis! π€©
π§ͺ
www.biorxiv.org/content/10.1...
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Stacey Ogden π¦
@labogden.bsky.social
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A big welcome to new postdoctoral fellow Rojalin Pradhan! She arrived from India last week and is getting settled in the lab this week - despite a wicked case of jet lag! π§ͺ π©π»βπ¬
0 replies 2 reposts 19 likes
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Stacey Ogden π¦
@labogden.bsky.social
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My partner told me this is the cutest picture heβs ever taken. I asked about all the pics heβs taken of me and our dogs over the yearsβ¦he thought about it for a bit and then saidβ¦ βYeah, I think itβs the raccoonβ.
0 replies 0 reposts 9 likes
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Stacey Ogden π¦
@labogden.bsky.social
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I have "Look What You've Done" by Jet stuck in my head. I need it to go away. π
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Stacey Ogden π¦
@labogden.bsky.social
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I just found out that #WoodpeckerWednesday is a thing, so here is a downy woodpecker from Memphis πͺΆ
0 replies 1 reposts 10 likes
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Stacey Ogden π¦
@labogden.bsky.social
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I thought the whole point of Target was the impulse purchase - which is unlikely to happen if the item is in a cage. Is this what Target means by: 'Secured shelves keep the items "on your list" in stock'? SMH
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Stacey Ogden π¦
@labogden.bsky.social
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In my experience, the response to reviewers is also not really doable until you know where all the new data and discussion will land in the text. I can draft out portions of it, but it doesn't feel productive until I can include a real call out - See new figure X and discussion on page Y π
1 replies 0 reposts 1 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Working on manuscript text revisions before all revised figures are assembled - yes or no? I try to revise as new data come in, but I'm beginning to think this is not an efficient way to work. It's a headache when multiple parts of the paper are in flux and requires more cleanup on the back end π§ͺ
1 replies 0 reposts 4 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Urban birding - hawk, coyote, and power lines πͺΆ
0 replies 1 reposts 7 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Happy Valentine's Day from the Ogden Lab! Here is a heart generated from a confocal microscopy image of a hooked primary cilium! Image from Lead Researcher Shariq Ansari @ansarishark.bsky.social SciArt DevBio π§ͺ π¬
0 replies 5 reposts 23 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Another Happy Mardi Gras offering - this is an E9.5 neural tube section that we are calling "Mardi Gras Beads" Olig2 is yellow, Pax6 is green, DAPI is purple. DevBio image by Ogden Lab Manager Miriam Dillard @miriamdillard.bsky.social! π§ͺ π©βπ¬
0 replies 1 reposts 14 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Happy Mardi Gras from the Ogden Lab! This is a confocal micrograph of MEF cells wearing their Mardi Gras colors! Nuclei - yellow; Cdc42 - green; Membrane protein - purple. Image from St. Jude grad student @christinaadaly.bsky.social π§ͺ π©βπ¬ π¬
0 replies 0 reposts 9 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Let's make Neural Tube Tuesday a thing π€ Here is a notochord (green, bottom) extending cytonemes (arrows) to the mesenchyme and adjacent neural tube floor plate (magenta with green). Cytonemes transport signals that instruct cell fate during neural tube patterning. π§ͺ Image by @erichall.bsky.social
0 replies 0 reposts 5 likes
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Stacey Ogden π¦
@labogden.bsky.social
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We can always count on @erichall.bsky.social to put the MAXIMUM amount of data on a poster π€£ π§ͺ
1 replies 0 reposts 11 likes
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Stacey Ogden π¦
@labogden.bsky.social
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I cleaned my office. It smells amazing and I have the Spotify Enya channel playing. My office has become a science spa. π§ͺ
0 replies 0 reposts 3 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Every time I've used the French press, it has been a hot mess...literally. After much experimentation, I finally settled on the pour over method. But I am curious to see this Gilmore coffee tiktok. π
0 replies 0 reposts 1 likes
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Stacey Ogden π¦
@labogden.bsky.social
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What are 5 topics you can talk about unprepared for 5 minutes? 1. Nervous system development 2. Henry VIII/Tudor history 3. Yoga 4. Strategies for reading the Game of Thrones series 5. Ways to brew coffee
2 replies 0 reposts 3 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Flashback to that time my lab gave Hedgehog "crystallography" a try π€ π π§ͺ
3 replies 0 reposts 68 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Thanks to Dr. Ben Allen from U. Michigan Cell & Developmental Biology for presenting a TERRIFIC talk in the St. Jude Cell & Molecular Biology Seminar Series! We really enjoyed your visit! Cool science and great meetings/discussions! π¦ π§ͺ
0 replies 0 reposts 5 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Water birds at Shelby Farms πͺΆ
0 replies 0 reposts 4 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Cell, Science, Nature
0 replies 1 reposts 1 likes
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Stacey Ogden π¦
@labogden.bsky.social
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I sometimes imagine I have a bullhorn and whistle for queuing up lab members to work on π§ͺ manuscripts:
π£Ansari et al #1 - UP! Ansari, Dillard et al #2 - ON DECK! Row et the GLI club - IN THE HOLE!
Hop to it @ansarishark.bsky.social, @miriamdillard.bsky.social and @sarayurow.bsky.social! ππ€£
0 replies 0 reposts 3 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Trainees: This is your occasional reminder that you should not get emotionally attached to your working hypothesis. You don't prove a hypothesis. You test it. π§ͺ π©βπ¬ π¬
1 replies 6 reposts 27 likes
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Stacey Ogden π¦
@labogden.bsky.social
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Happy #MicroscopyMonday! Here is my artistic oil paint rendering of a scanning electron micrograph of neuronal cytonemes. Original image was acquired by @erichall.bsky.social in the St. Jude Cell and Tissue Imaging EM core. See his artistic rendering in the quoted post π§ͺ
0 replies 0 reposts 7 likes
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Eric Hall
@erichall.bsky.social
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Check out this solarized SEM of the neural tube lumen with added hedgehogs! In our latest work from the @labogden.bsky.social lab we found cytonemes carry Sonic Hedgehog proteins across the neural tube for cell fate patterning. Check out the paper! www.cell.com/cell/fulltex...
0 replies 2 reposts 2 likes