Shauna Paradine's avatar

Shauna Paradine

@paradinelab.bsky.social

87 followers 36 following 48 posts

Assistant professor in organic chemistry at University of Rochester. Lovers of catalysis, building molecules, and all things science. Also running, hiking , gardening, old houses, and DIY.
Professional Website: t.co/GIl5vEPuOP


Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Time to make elderflower cordial over here!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Switch the site-selectivity of your carbofunctionalization reaction with this one weird ligand!
Lots of fun to build on this completely unexpected result, this project took us into data science and modeling to learn about the selectivity we were seeing. Check it out!
www.nature.com/articles/s41...

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Thank you for highlighting the paper, it was such a fun project 😊 A reminder that I need to post this to my own account too!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Love to see current and former students meeting each other at conferences! Dynamo 4th year grad student Cay at left and former undergrad Jisoo (who has been rocking it in @levinchem.bsky.social 's lab) at right, at the Heterocycles GRC

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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You should be either neutralizing the compound causing the smell in the hood (e.g. sulfides, thiols) or rinsing glassware in the hood and caring for the waste accordingly. If the glassware is still stinky after that I guess I'm stumped!

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Reposted by Shauna Paradine

Fiona McMillan's avatar Fiona McMillan @moraigmonkey.bsky.social
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Sharing from that other place because this is actually important. Audrey Cameron is looking for deaf chemists to contact her.
ChemSky

x.com/aud2526/stat...

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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full disclosure: I feel strongly enough about this that I created a whole class on communication for chemists in my department

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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We really don't spend nearly enough time teaching students how to effectively communicate and it shows - and posters are often some of the worst offenders (and not just from us organic chemists). We really need to incorporate this more into our curricula

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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It's pretty ridiculous that students are only given the option to buy, especially since my institution rents regalia for the faculty every graduation (at no cost to us) - a rental market clearly exists!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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If the smell is escaping your lab, that's a real problem - either a failure of lab ventilation, a spill, or negligence in handling a compound. So yes, I would worry.

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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My lab holds that if you're smelling a chemical, that's an exposure and should be avoided, even within the lab. Smelly compounds in particular we handle exclusively in hoods (in-hood rotovap, weighing compounds using sealed, tared vials, etc).

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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It's either "oh, I hated chemistry in high school" or "oh, you must be so smart" and I hate both of those responses for different reasons

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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My undergrad organic prof uses this as a metric for choosing doctors - if the doctor says they HATED organic chemistry, she finds another doctor

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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So exciting to see the complete work out in the world, way to go to you and your lab!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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I love this (and a lot of other things) about hoyas, once they decide to push out a new vine they go gangbusters. That hoya is gorgeous btw!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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A representative selection of the daffodils currently blooming in my yard

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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There was an annular eclipse on May 10, 1994, which I remember well from elementary school (I lived in the path of, uh, annularity? - so got the full effect of inside recess and going out in groups to see the eclipse through a pinhole)

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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I have not come across this yet and I hope I never do

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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You missed a real special eclipse in Rochester

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Just a little research group update: we've had a lot of new faces here recently! We're thrilled to have Lauren Morano, Livan Borrego, and Neively Tlapale Lara as new 1st years. Roberto Leon Baxin (3rd year) also joined our group in the fall. Look out for great things to come from all soon!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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They did - once a proper investigation brought this all to light, UR removed the grad students from the lab and made sure they found homes in other labs. So, at least they did right by the students once they realized what was happening (late, I know, but still).

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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It took too long to do a proper investigation (and boy, did they drag their feet), but to UR's credit at least, once they did, they removed all the grad students from Dias' lab and worked to make sure they all found good homes in other labs. In the end, they protected the students.

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Double your pi bonds, double your fun 👯‍♀️ Check out our group's first review, now out in Angewandte Chemie! We pulled together highlights of recent developments in transition metal-catalyzed reactions of dienes. Lots of cool stuff to feature!
onlinelibrary.wiley.com/doi/10.1002/...

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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You could always mark it and dig up the bulbs in the fall to plant in a sunnier spot - or just leave be if you don't feel like it, they won't be the happiest, but they'll be ok.

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Is that a bit of a shady spot? Flowers will sometimes flop if they're in more shade than they'd like (stems don't grow quite a stout and strong).

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Ha, Rochester has more shared instrumentation and resources in our chem department than Harvard had - and you definitely have us beat too! How I wish we had a glassblower 😭

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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5th year grad student Dasha spent last summer doing a DAAD-RISE internship at BASF, and applied her strong column chromatography skills to develop a new technique for extracting microplastics - and just published a paper on it! Check it out: www.sciencedirect.com/science/arti...

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Every time there's a winter weather warning we get an email saying, "we're closely monitoring the weather but remember that as a rule we don't close, and plan to maintain normal operations except in extreme weather." Given it's Rochester, the bar for "extreme weather" is very high

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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I'm teaching a smaller version of our intro organic (60 students vs. 350), but the DFW rate is less than 10%, and I expect it's not more than 10-15% for our larger course. 50% is a ludicrous number.

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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One of my grad students referred to a paper from 2005 as being from "around the turn of the century" in their dissertation and I was like, absolutely not

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Thrilled that third year grad student Roberto Leon Baxin was among the winners of the Walters Teaching Award. Huge congrats to him and to all the other winners at our fall awards ceremony yesterday! 🎉

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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I questioned this career path when I saw the toxicity, but then realized that the same freedom that lets some get away with treating students and others poorly also lets me create the environment I want in classes and research, and change the culture of our field through my students (even if small)

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Working with students, hands down - and being in the position where I can create a safe and welcoming environment where students thrive and feel supported as they challenge themselves and grow as students and scientists, and being witness to that growth

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Brought my little one to campus in the morning (my spouse and I met there!), and showed her the science complex, but predictably she was more interested in the dino skulls than my old research lab 😆 (she loved the periodic table display with element samples, so maybe there's hope yet 😉)

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Returned to my alma mater, Albion College, to give a research seminar on Friday. It was so special going back to where it all began, and to see many of the professors who inspired, encouraged, and supported me (and still do 15 years later!). 💜💛

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Had the opportunity to visit Eli Lilly today and interact with an incredible group of scientists throughout the day, and shared my group's research too. Very grateful for the invitation, I loved my visit!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Leaf peeping with a purpose 🍂 had a great visit to Colgate today, such wonderful students and faculty. PUI visits are some of my favorites (hi, alum of a PUI here, I am not biased at all).

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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A few group members (plus an honorary group member) went for a hike over the weekend - so many good nature trails around Rochester!

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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I learned this after I told my class to download ChemDraw and they told me the link on the university IT website wasn't working (the link was to the Perkin Elmer site that I guess exists no more), good times

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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It's required in New York now! Our ad this year had the salary range (and I would like to see this required everywhere)

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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I technically went, but not to my school's prom, I went with a group of friends from my math and science center to their high school's prom. We did each other's hair, went to dinner, hung out at the prom for a bit then stayed up late and watched movies. Way more fun than normal prom.

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Want to join our AWESOME department in beautiful Rochester, NY? We're hiring a tenure-track faculty member in organic/chem bio, broadly defined, at all levels. Apply here 👇
www.rochester.edu/faculty-recr...

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Favorite element: manganese Favorite reaction: Catellani Reaction Favorite het: piperidine Favorite functional group: amine Favorite piece of glassware: fritted filter funnel Favorite natural product: erythromycin

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Also, while transition metal catalysis has my heart, I've been tinkering with some biocatalysis, and I just say the experimental analysis is much better tastier

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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In addition to bringing in my group's first major grants, this summer I took on something even more ambitious: removing some lawn to build extensive raised beds and a terraced garden wall. Those spatial reasoning skills were definitely handy for building a dry-stack stone wall

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Ok, moving my group's account from Twitter to Bluesky was a bit soon, so I'll take this excuse to jump into chemsky as a whole person rather than my group's PR (though I'll ALWAYS highlight all the awesome things my students are doing!). So, hi everyone 👋🏻

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Shauna Paradine's avatar Shauna Paradine @paradinelab.bsky.social
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Coming into bluesky with some good news - our group has been awarded an NIH MIRA! We're excited for the funding and for the flexibility the MIRA gives us to follow the science wherever it may take us.

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