I always feel weird when that happens, and I have cut back on replying outside my own timeline a bit (I figure anyone who replies to me on my account knows what they're in for), but I don't avoid *all* replies because then I'm that asshole who never replies elsewhere, etc.
But really, the "block anyone you don't vibe with" attitude around here is pretty helpful. I can feel a bunch less guilty about it because the block is just *so* effective.
This kind of happened to me the other day when I quoted you, but that conversations went everywhere in wild and interesting ways. I appreciated it. (It was about our perception and connection with words--I brought up grey/gray and it went places. It was fun.)