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Tatiana Dimitriu@tatianadimitriu.bsky.social |
New preprint on the interactions between conjugative plasmids and defence systems (restriction-modification systems), with Mark Szczelkun and Edze Westra #MicroSky
www.biorxiv.org/content/10.1...
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Alex Crits-Christoph
@acritschristoph.bsky.social
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This was a great read! We were really looking for data on some of these exact questions from a synthetic biology context.
0 replies 0 reposts 1 likes
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Tatiana Dimitriu
@tatianadimitriu.bsky.social
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We asked how efficient RM systems are against plasmid conjugation in E. coli. We found a lot of variation depending on RM system and plasmid combination, but on average, restriction was not very strong! For a rough summary of the patterns we observed (but see the preprint for more):
1 replies 0 reposts 2 likes