Nick Holmes's avatar

Nick Holmes

@thehandlab.bsky.social

127 followers 144 following 83 posts

handy neuroscientist | touch & movement | brain stimulation | neurobiography.info | pod host @ theerrorbar.com | tms-smart.info | researchintouch.info | b. 335ppm CO2 | pro birds | Associating with Professors since 2023


Reposted by Nick Holmes

Paris Marx's avatar Paris Marx @parismarx.bsky.social
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Google’s emissions are up 48% in 5 years. Microsoft’s are up 30% since 2020. Those soaring figures are being driven by mass investments in data centers to power AI tools. Generative AI is a climate disaster and data center expansion must be stopped.

22 replies 1104 reposts 1829 likes


Reposted by Nick Holmes

Andrew D Wilson's avatar Andrew D Wilson @adw.bsky.social
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If you want to know about my main source of work stress, then read this. UK HE is in crisis and we don’t have a lot of options for how to deal with it, and it’s serious and it matters

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Very good, thank you. The Times newspaper is rightly singled out as the worst offender of the UK press. I've seen so much anti-university bilge there over the last decade.

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Reposted by Nick Holmes

Anastasia Christakou 💙's avatar Anastasia Christakou 💙 @christakou.bsky.social
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We are looking for our next CINN Research Fellow, a postdoc with neuroimaging experience. Excellent research resources, training and mentorship, structured opportunities in management and support. Fixed-term with the possibility to extend.

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Yeah, i had some pretty thrilling wet paint drying on the wall - i kept checking back and forth!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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And why weren't ypu watching the football, huh? 🤔

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Right, you can *invent* a narrative post-hoc that explains why an applicant might do that, & use that to help reject. But it's fiction. Solution: put an explicit tick-box in the application form; devise faie assessment criteria. UK students are so much better served by rubrics than UK academics!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Haha, yes. I think this is the 'classic' model for those who have consecutive, perpetual funding. Glad my work is cheap!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Ooh, that's good! I always wondered who my listener was! 🙏

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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When reviewing #grant applications, do you assume that applicants *need* the money to do the proposed work?

Got some feedback that reviewers weren't sure if the work described 'would happen anyway without funding'.

Pretty astounded TBH - who wastes weeks of time writing unnecessary applications?

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Reposted by Nick Holmes

Joe Bak-Coleman 's avatar Joe Bak-Coleman @jbakcoleman.bsky.social
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The replication crisis is often described as a crisis of false positives, but is it?

In our (re)new(ed) preprint, we show that false positives do not explain the replication crisis, and that varying rep. rates are often explained by replication sample size. #metascience

osf.io/preprints/so...

5 replies 41 reposts 94 likes


Reposted by Nick Holmes

Reposted by Nick Holmes

Katharine Hayhoe's avatar Katharine Hayhoe @katharinehayhoe.com
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“Many governments restrict or prohibit advertising for products that harm human health, like tobacco. I urge every country to ban advertising from fossil-fuel companies. And I urge news media and tech companies to stop taking fossil-fuel advertising.” - Antonio Guterres YES!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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🙏 It's in my head, and partly written. Coming...

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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🙏 Much in debt to to your good self! References in Part III

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Thank you! I should really have given some readings & cited your work too - will do that in Part III. Yeah, some sensible ideas & stats mixed up with lazy mis-readings of the target articles & gross generalizations. Deflating!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Yeah, this is top of the list! I try to put the axes up first, & explain them before the data appears. I even put 'good' & 'bad' labels on axes if it helps (eg, performance on test) Across the talk/poster, use the same colour schemes & notations, same formats for graphs. Minimise audience work!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Aha. Yes, then only #1. Good luck!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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one additional comment, after several days thinking: Does "statistical challenges and misreadings" apply to the target article or is it a summary of the commmentary? Genuinely hard to tell.

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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in case it helps with any revision: my annotations on your commentary.

I found it problematic in a number of ways. this contribution does not increase my confidence in open science/reproducibility; it feels like the authors are dumping on a study to promote a particular approach.

osf.io/x394k/

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Reposted by Nick Holmes

Olivia Guest · Ολίβια Γκεστ's avatar Olivia Guest · Ολίβια Γκεστ @olivia.science
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Deadline approaching. Please apply soon to not be last minute and get unduly stressed. 😊

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Happy to go into more detail when i have some more time, but i did not like this approach to commentary.

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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I am not defending the target article, & have not read it. This was a difficult read. Many assumptions of the authors seem to have been imposed onto the target article. There's much to disagree with in specific places (eg: 'preregistered work is harder', N=84 is 'very small'; t>3 is a small effect).

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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1. Do all the controls 2. Be your worst critic: do harsh, critical work to refute your ideas 3. Don't exclude *any* data; model it 4. There are *no* statistical rules that apply in all situations (N, p, effect size etc) (apart from #3 ;-))

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Reposted by Nick Holmes

Jon Peirce's avatar Jon Peirce @peircej.bsky.social
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Job opportunity with the PsychoPy/Pavlovia team (Open Science Tools) Please share with any software developers you may know 🙏 OST are a small team and finding great team members is absolutely essential to our ability to build high-quality tools

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Just middle England during a solar storm (crappy camera, but the best-ever Northern Lights i've seen)

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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The UK does not formalise the 'counteroffer' process re: academic promotions. I'm sure that means it's all fine, right?

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Phew: i scored 24.5/25 in that test - only took me 30 years to beat the bias out of my brain!

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Reposted by Nick Holmes

Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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I know there's lots going on, but holy shit, ocean temperature 😮

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Good luck! It's quite the task. (Should axes begin at 1 on bar plots 🤔)

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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not seen this before: in an otherwise very good paper, some of the datapoints (on the right of this image) have been... shifted! likely a post-plotting image editing problem. (symbols are different group means, dotted lines show 95%CIs on log scale, offset from means so all data can be seen)

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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I'm 7/8ths of the way through extracting data for a #TMS #meta-analysis (~400 studies). I originally planned to be finished in November (2023).

Gantt Charts are fiction.

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Reposted by Nick Holmes

Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Yeah, that's my guess, bit i am no expert on T-ES literature or methods (tdcs, trns, tacs). At least we know that TMS can effectively stimulate the brain (it can and does induce seizure). But effective stimulation is even argued about for T-ES.

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Reposted by Nick Holmes

Jay Patel's avatar Jay Patel @infotainment.bsky.social
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🤔 How hard is it to run a successful crowdsourced peer review platform?

😮 Well, PubMed Commons failed (.02% replies).

It reminds me of recent platforms that have failed or caught minimal attention. Solving post-publication peer review requires creative thinking.

#Metascience #peerreview

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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I post quite a bit on pubpeer - also failed?

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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No comment your honour! I've only ever looked at cog-neuro/psychophysics & physiology papers (of which there are 000s), & have stayed well clear of 'plasticity' & therapeutic applications - I'm super-skeptical by default, & if problematic, that tanker would take a lot of turning 🙈🙉🙊... Cheers!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Had no idea this existed, yet i use Pubmed 10-20 times a day. Tough gig!

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Happy #Election2024 day in the UK!

The nasty party of Johnson, Truss & Sunak is being cut down by half.

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Nick Holmes's avatar Nick Holmes @thehandlab.bsky.social
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Effect size for interfering with tactile *discrimination* with TMS over S1 is large and consistent across experiments. For interfering with tactile *detection* it is small-to-medium & less consistent (highest heterogeneity). A wider meta-analysis of well-controlled studies is needed. cheers! Nick

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