Really exciting stuff happening in oncology, y'all.
A doctor with glioblastoma—an aggressive brain cancer that kills most patients less than a year after diagnosis—has now been cancer-free for a year, thanks to a world-first personalized vaccine.
Really oddly bittersweet to see personally, because I have a (relatively young, younger than this guy) friend who died of this relatively recently. But I'm glad other people don't have to live through it. I just wish he'd have had the chance to be vaccinated
The article fails to mention this is done with mRna which is really weird.
Friend of mine is a genetic researcher and said the mRna/Crisper combo is one of the biggest advances since the discovery of antibiotics.
My wife's been undergoing treatment for glioblastoma for about 6 months, and what I'd add from experience is that the current state of treatment is pretty amazing, but glioblastoma is an unpredictable type of tumor. Having another treatment to add on top of the others is a welcome change.
Vaccines trained to fight an individual patient's specific cancer have been the Holy Grail of oncology for years, and now this, coupled with the recent bladder cancer vaccine, may be the first hints of an amazing future.
One of the best people I have ever known died earlier this year from complications related to glioblastoma. The sooner it's a solved problem, the better.
My husband worked for a company that was working on Dr. Scolyer's melanoma research. He shared an earlier article on this with me just yesterday. Interesting how fast the research happens when YOU are the one affected huh? Incredible stuff though.
That's semi great news.
I say semi great because anyone in the US who has dealt with medical issues know its going to be fucking super expensive and out of reach to us normal working folks, even with insurance.
OMG. I wish this had been around a few years ago - glioblastoma is what killed my father-in-law. He was a brilliant, fantastic man, it it hurts horribly that he's gone.
I'm glad others in the future won't have to suffer like he did and we have.
Exciting, and not just for cancer patients. This would crack a lot of stuff wide open.
I've said for a while that when we cure cancer that the "curing cancer" bit will historically end up as a footnote.
An honest question about diagnosis vs end of life question. My mom had her 1st exploratory brain surgery (1974) and wasn't diagnosed until 1980, 2 previous surgeries in '78 and '79. She died in 81. Is the detection rate better now?
This stuff gives me hope. Retinal degeneration is a genetic thing in my family. My grandmother had ocular cancer, started going blind in her 60s. My mom hasn't started yet, but it's there, I have the mutation as well.
This kind of research could someday save my eyes!
Given that the rates of glioblastoma have shot up (relatively; it’s still a rare cancer compared to GI or reproductive related cancers, but it’s seen a 7-10x increase in diagnosis), this is amazing.
(And brain cancers terrify me like no other.)