Oh my god, this is fucking huge. It was huge when we developed a daily PrEP pill that could prevent you from catching HIV; this is a successful phase III trial of a PrEP shot that will only need to be given *twice a year*. Still needs a confirmatory Phase III, but holy fuck.
And at one time this news would have been the lead story on every newscast and every publication. I supose it's a mark of how much HIV has been defanged that it has received relatively little attention.
Part of a South African study abroad test group in โ99. US universities still cautious due to Amy Biehl.
We all had to do a project. Mine was on the AIDS crisis, where mothers were being denied meds to prevent transmission of HIV to the baby.
Dr Zuma and, later, Mbeki have so much to answer for.
This is great. Apretude is awesome, but I have to go in every 2 months. Right now it puts me in almost exactly at Christmas and my birthday. The price for being an early adopter, I suppose. Two times? Yes!
This really is immense on several levels. Not just for HIV, but when it comes to developing further protection from the negative effects of viruses in general, including COVID. Even PrEP was a huge step forward and still relatively new.
as an 80's kid i'm still just flabbergasted that this is a solved problem. it really seemed like we would never see the day. this is up there with closing the ozone hole
We could be the last generation to even live with HIV.
Gilead, do the right thing, please. Make tiny, tiny profits on each shot and make it available for a globally attainable price. 8 billion shots twice a year still brings in a lot of money for many, many years.
If this is fully validated and the efficacy is consistent, then it's far beyond just HIV. The ramifications of such a significant advance are huge. I just hope that governments don't(as they usually do) allow corporate greed to take precedence over human need.
Phase III is so important. Iโve been on the end of conference calls where the CRO/pharma company is explaining how the data didnโt meet what was required in terms of significant results, and seen so many similar reports and closures now that Iโm in regulatory work. But this is hopeful.
Thinking of my friends in the early 90s WHO WOULDN'T EVEN HAVE SEX BC OF TRANSMISSION and wishing they were young and horny in a better time (for meds, at least).
Good news.
We hoped for a "cure" way back in 92, when we lost Tom MacDonald, my older brother, who cared for me and who I miss.
He would say "Well we can't dance and there are no ..."
Bravest person I've met.
Good Lord, if it works as it seems to this could mean the end of HIV/AIDS in a decade or two. These researchers deserve a Nobel prize, or whatever medical researchers get.